Eric manes blood disease

Enhanced oxygen utilization and blood flow, especially to the liver and non-exercising skeletal muscle, may enhance lactate clearance. This may allow athletes to maintain a higher intensity of exercise, while the reduction of oxidative stress from high intensity exercise may delay fatigue ( Adams & Welch, 1980 ; Brooks, 1985 ; Mizuno et al ...

Eric manes blood disease. diseases. Research with LM is being focused on treat-ment for dementia, cognitive deterioration, Parkinson's disease, and Alzheimer's disease. There is great interest in the potential of using LM to improve brain function (3, 5, 11). Lion's Mane has been shown to activate macrophages— key cells in the innate immune system and neuro-

Lion's Mane. Lion's mane, Hericium erinaceus, is a culinary and medicinal mushroom. Lion's mane appears to have neuroprotective and antioxidant properties in the brain. Lion's Mane is most often used for Brain Health. The Examine Database covers Alzheimer's Disease,Anxiety, and 3 other conditions and goals. Lion's Mane is linked to 5 ...

Moonshiners: With Jeremy Schwartz, Josh Owens, Eric 'Digger' Manes, Mark Ramsey. Follows a diverse group of people living in Appalachia who carry on a 200-year-old tradition passed down from their forefathers, making moonshine.Call 310-784-6954. Dr. Eric Milefchik is board certified in internal medicine and infectious disease. He received his medical degree from the University of Toledo College of Medicine and completed his residency training at LAC-USC Medical Center in Internal Medicine and at New York University Medical Center in Neurology.2.3. Experimental Animals. Healthy male and female Sprague Dawley rats aged 6 to 8 weeks and weighed between 180 g and 200 g were used in the study. The female animals used were nulliparous and nonpregnant. Food and water were provided ad libitum.The animals were kept at 27°C (±2°C) and a 12 h light/dark cycle was maintained throughout the experimental period.According to Dr. Colin Colby, Eric either has some kind of cerebrovascular disease– defined by the Cleveland Clinic as a condition that affects blood flow to the brain–like TIA (transient ...Gum disease begins when the sticky, bacteria-laden film dentists refer to as plaque builds up around teeth. A completely different type of plaque — made of fat, cholesterol, calcium, and other substances found in blood — can build up inside arteries. Known as atherosclerosis, this fatty plaque is the hallmark of coronary artery disease.Anemia results from a decreased number of red blood cells or hemoglobin—the protein that carries oxygen. It can also result from iron deficiency, sickle cell disease, or thalassemia, as well as a number of other conditions and diseases. Polycythemia vera is a condition in which the bone marrow makes an excessive number of red blood cells ...

Lion's Mane in nature is found growing off the dry bark of trees (Kuo, 2016). ... degenerative diseases of the brain, and help prolong life. ... are protein which are too big to fit through the blood-brain barrier that would allow for nerve development (Bing-Ji, 2010). As explained by the article, "Blood-brain barrier permeability andBlood cancer symptoms vary based on blood cancer type, but there some symptoms all three have in common: Fatigue: This is feeling so tired you can't manage your daily activities. You may also feel weak. Persistent fever: A fever is a sign your body is fighting infection or responding to abnormal cancer cells.The goals of treatment for small vessel disease are to control the narrowing of the small blood vessels that can lead to a heart attack and to relieve pain. Medications for small vessel disease may include: Nitroglycerin (Nitrostat, Nitro-Dur). Nitroglycerin tablets, sprays and patches can ease chest pain by relaxing the coronary arteries and ...Lion's mane mushroom provides many health benefits, but there are two plant compounds (hericenones and erinacines) in particular that are neuroprotective. Experts say these plant compounds found in lion's mane can generate new brain cells and protect against neurodegeneration associated with Alzheimer's and Parkinson's diseases.Erdheim-Chester Disease. Erdheim-Chester disease (ECD) is a rare blood disorder that occurs when your body makes too many white blood cells called histiocytes. ECD can affect multiple organs and cause various symptoms or even no symptoms, making diagnosis tricky. Current treatments include targeted therapy, immunotherapy and chemotherapy.Sickle cell anemia is caused by a change in the gene that tells the body to make hemoglobin. Hemoglobin is the iron-rich compound in red blood cells that allows these cells to carry oxygen from the lungs to the rest of the body. The hemoglobin associated with sickle cell anemia causes red blood cells to become rigid, sticky and …Erica Manes. See Photos. View the profiles of people named Eric Maness. Join Facebook to connect with Eric Maness and others you may know. Facebook gives people the power to...

While his valiant battle against the disease, marked by ongoing dialysis treatments became public, fellow moonshiners Mark Ramsey and Digger Manes shared poignant photographs of him in a nursing home. Hedrick, a legendary moonshiner, master storyteller, and still maker, earned renown as one of the most skilled moonshiners in Appalachia.Blood Disease & Disorders Resources. The Blood Diseases & Disorders Education Program offers resources for health and community professionals to educate patients, their caregivers, and the public about blood diseases, blood disorders, blood donation and safety.Immune thrombocytopenia (ITP) is a type of platelet disorder. In ITP, your blood does not clot as it should, because you have a low platelet count. Platelets are tiny blood cells that are made in the bone marrow. When you are injured, platelets stick together to form a plug that seals your wound. This plug is called a blood clot.Eric “Digger” Manes’s Net Worth And Salary. Eric Manes, aka Digger, is famous for appearing in the television show Moonshiners. He was born in 1974 in Tennessee. His father owned an embalmer, where he worked as a licensed embalmer. As per sources, Digger started his moonshining business at the age of eighteen and actively worked on it.

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Erdheim-Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non-Langerhans-cell histiocytosis).It was declared a histiocytic neoplasm by the World Health Organization in 2016. Onset typically is in middle age, although younger ...Enhanced oxygen utilization and blood flow, especially to the liver and non-exercising skeletal muscle, may enhance lactate clearance. This may allow athletes to maintain a higher intensity of exercise, while the reduction of oxidative stress from high intensity exercise may delay fatigue ( Adams & Welch, 1980 ; Brooks, 1985 ; Mizuno et al ...The first coagulation factor genes to be sequenced were the genes implicated in the common severe inherited bleeding conditions, hemophilia A and B. 1, 2 Very quickly, after the cloning of the F8 and F9 genes, strategies were initiated to incorporate this new information into hemophilia carrier testing and prenatal diagnosis. 3.No. Mark Ramsay and Eric 'Digger' Manes are still members of the Moonshiners cast in 2023. The two appear in season 12, which kicked off on November 9, 2022. In the upcoming episode airing February 8, Mark and Digger let Beaz join their operation. So it seems as though they're continuing with their moonshining efforts.The most common Ashkenazi genetic disease is Gaucher disease, with one out of every 10 Ashkenazi Jews carrying the mutated gene that causes the disease. Doctors classify Gaucher disease into three different types, resulting from a deficiency of glucocerebrosidase (GCase) within the body. Type 1, which is treatable, is the most common form among ...Rosai-Dorfman-Destombes disease (RDD) is a rare non-Langerhans cell histiocytosis (LCH) first described in 1965 by a French pathologist, Pierre Paul Louis Lucien Destombes, who reported 4 children and young adults with lymphadenopathy and sinus histiocytosis upon histologic analysis. 1 Four years later, Juan Rosai and Ronald Dorfman analyzed 34 cases of the same entity under the name sinus ...

When it was diagnosed 25 years ago, it was called an "orphan disease," meaning the small number of people affected didn't justify research investments by major pharmaceutical companies ...Mar 21, 2024 · Digger manes blood disease is most commonly seen in young dogs, and it can be fatal if left untreated. Treatment typically involves blood transfusions and medications to manage the symptoms. Digger manes blood disease is a serious condition, but it can be managed with proper treatment.Lions mane is shown to promote neurogenesis. Parkinsons is a disease of neuronal cell death. Lions mane and Parkinsons are in direct opposition to one another: one promoting growth and the other decay of nerve cells. You can draw your own assumptions about lions mane and its efficacy in treating Parkinsons disease.Mark Ramsey. Mark Ramsey grew up exploring the woods of East Tennessee. He was introduced to a local moonshine expert as a young man and mastered the trade through hands on experience. He and his distilling partner, Digger Manes, now carry the storied craftsmanship forward with their distinctly delicious recipes!In the United States, people with the disease typically don't live past 50. However, the faulty β-globin gene remains unexpectedly common in parts of the world where malaria is prevalent. That's because people with just one defective copy of this version of the gene gain some protection from malaria, although researchers aren't sure how the ...Sep 3, 2020 · As shown earlier, polygenic contributions can yield effect sizes on blood traits comparable to or larger than that of known monogenic variants. We therefore sought to explore whether they affect predisposition to rare diseases of the blood. In UK Biobank, we extracted ICD10 codes for a total of 29,080 patients and controls, with 423 blood diseases.According to the USDA, a 100-gram serving of lion's mane mushrooms provides about 43 calories, 2.5g protein, 7.6g carbohydrate, and 0.3g fat. A 100-gram serving is about one-half cup. Vitamins include small amounts of thiamin, niacin, vitamin B-6, biotin, and folate.Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. Typically, only one ear is affected initially, but over time, both ears may become involved. Episodes generally last from 20 minutes to a few hours. The time between episodes varies.Addison's disease symptoms usually happen slowly, often over months. The disease can move so slowly that people who have it may ignore the symptoms at first. Then a stress, such as illness or injury, makes symptoms worse. Symptoms may include: Extreme fatigue; Weight loss and loss of appetite; Areas of darkened skin; Low blood pressure, even ...Click the CC icon in the bottom right of the video to activate captions. To choose a different caption language: At the bottom right of the video, next to th...

Request an Appointment for Pediatric Blood Disorders. The information you provide will enable us to assist you as efficiently as possible. A representative will contact you within one to two business days to help you schedule an appointment. To speak to someone directly, please call 773-702-6808. If you have symptoms of an urgent nature, please ...

Digger manes blood disease is a rare, inherited blood disorder affecting dogs characterized by an abnormally low number of red blood cells leading to anemia.. Dogs that are affected are often severely anemic, with a reduction of more than 50% of the red blood cell count. This lack of oxygen-carrying cells causes significant health issues and usually leads to death before the dog reaches one ...Chronic kidney disease and other chronic diseases often block iron from traveling to the bone marrow, where it is needed to make red blood cells. Mechanistically, chronic inflammation has a tendency to shut down ferroportin, the only protein that allows iron to pass from inside of cells to the outside, where another protein called transferrin ...Eric Manes, a well-known public figure, has been open about his health struggles and the impact they have had on his life. Through his candid sharing, he has inspired many others who may be facing similar challenges.A PE can occur when part of a clot detaches and travels to the heart or lungs. If this happens, the fragment can cause a new clot, block blood flow, and interfere with gas exchange in the lungs. A ...Blood-clotting problems. Diseases and conditions that increase your risk of blood clots may increase your risk of intestinal ischemia. Examples include sickle cell anemia and the Factor V Leiden mutation. Other health conditions. For example, having high blood pressure, diabetes or high cholesterol can increase the risk of intestinal …Education / Family. There is no personal information available about Eric "Digger" Manes. All we know is that he was born and raised in Newport, Tennessee, USA. His father owned a funeral parlor where Eric assisted his father as an embalmer. He is an educated person, but his background is not shared over the internet yet.The alternate variant for this address is 226 Curve Strt, Newport, TN 37821-3608. The ZIP code for this address is 37821 and the postal code suffix is 3608. Coordinates for your route planner: 35.9642681,-83.1847248. The expected price of renting a two bedrooms in the 37821 ZIP code is $730/month. $663/mo is a fair market rent value set by HUD ...Moonshiners season premiere revealed that star Digger Manes had a rare blood disorder. This caused fans great concern, so Digger took to Facebook to let fans know what was going on. He has a form of leukemia, and while it is not a lethal version of the disease, it is still serious.Eric Digger Manes . A legendary moonshiner , he has been in business for about 40 years producing top notch brews and wines. Born around 1974 in Newport, Digger helped his father in the funeral parlour. ... This season Digger would be seen getting nervous regarding his mother's health, a rare blood disorder. Eric Digger Manes (Discovery) Mark ...

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... Manes C, Ionescu-Tirgoviste C, Witte DR, Fuller ... disease and normal blood pressure: the CAMELOT study: a randomized controlled trial ... Eric J.Topol - NEJM ...In a study published in June 2020 in Frontiers in Aging Neuroscience, people with mild Alzheimer's disease who took three 350 milligrams (mg) capsules of lion's mane daily for 49 weeks saw ...Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. At end of 2013, over 300,000 Japanese patients had maintenance dialysis therapy (JSDT). In Japan, the major causes of end stage kidney disease (ESKD) are chronic glomerulonephritis (particularly IgA nephropathy ...Digger Manes is sick and was diagnosed with a blood disease raising concern among his fans, so let's clear it up from the following article. Disclaimer. Ethics Policy ...No. Mark Ramsay and Eric ‘Digger’ Manes are still members of the Moonshiners cast in 2023. The two appear in season 12, which kicked off on November 9, 2022. In the upcoming episode airing February 8, Mark and Digger let Beaz join their operation. So it seems as though they’re continuing with their moonshining efforts.Digger Manes is sick and was diagnosed with a blood disease raising concern among his fans, so let's clear it up from the following article. Disclaimer. Ethics Policy ...The reality TV star will probably pass on the time-honoured practice to his child- we expect to see his young lad on the show. Reality TV star facts report that Moonshiners Eric “Digger” Manes has a net worth of $300,000. With their ever increasing popularity, his net worth is expected to surge in subsequent years.Imagine stumbling on to what looks like metal trash in the middle of the woods. On our exclusive clip for tonight’s enthralling edition of Moonshiners, show stars Digger Manes and Mark Ramsey ...Dec 1, 2021 · Champagne or Shine Pain?: With Eric 'Digger' Manes, Mark Ramsey, Mike Cockrell, Jerry Benson. ….

Popcorn's Secret Stash: With Jeremy Schwartz, Mark Ramsey, Eric 'Digger' Manes, Pam Sutton. Ten years after Popcorn Sutton's death, his widow reveals a clue that could lead Mark and Digger to a hidden stash; Mike must gin up his brandy game to pay off his debt to Mark and Digger; Donnie and Teresa build a still site in a Kentucky …Introduction. Next-generation sequencing (NGS) of disease probands and their parents has propelled the discovery of monogenic causes of autoinflammatory diseases 1, that present with severe, perinatal-onset, systemic, and organ-specific inflammation.Tissue infiltration by activated innate immune cells, including monocytes, …Hematohidrosis is a rare condition characterized by blood oozing from intact skin and mucosa. Signs and symptoms include sweating blood, crying bloody tears, bleeding from the nose, bleeding from the ears, or oozing blood from other skin surfaces. The episodes are usually self-limiting. In some cases, the fluid appears to be blood tinged, while ...Eric and Sookie run for their lives after watching Bill consume Lilith 's blood and be reborn from a pool of blood. They reach the elevator shaft, but get stuck when Bill shuts down the power to the building. Using Sookie's light as a torch, Eric punches through the roof of the elevator. They confiscate an SUV and pick up Pam, Tara, Nora ...Manes may be derived from "an archaic adjective manus—good—which was the opposite of immanis (monstrous)". [5] Roman tombstones often included the letters D.M. , which stood for Dis Manibus , literally "to the Manes", [6] or figuratively, "to the spirits of the dead", an abbreviation that continued to appear even in Christian inscriptions.This is a good way to find out whether there are abnormal white blood cells during the growth of children, which greatly reduces the risk of children suffering from diseases. Acknowledgments This work was partially supported by the National Key R&D Program of China (grant no. 2019YFE0126200) and National Natural Science Foundation of China ...Eric Manes is a feature film and television writer and producer, owner of Swiss chocolate company Coco Suisse with his wife Marianne Manes, and a State of California Registered Investment Advisor. Manes produced the documentary Voices of Iraq, for which he funneled digital video cameras to hundredscool the blood, a telephone switchboard and a supercomputer. But the brain is much more complicated than any of these, a fact scientists are confirming almost daily ... Eye Disease 80,000,0001' S 16 billion hs thins. and the erebellum Hearing Loss 28,000,000 56 billion ss hir h helps t ontrol mos ement Eric manes blood disease, Aug 29, 2012 · Muscle 2-Volume Set. : Joseph Hill, Eric Olson. Academic Press, Aug 29, 2012 - Science - 1528 pages. A valuable study of the science behind the medicine, Muscle: Fundamental Biology and Mechanisms of Disease brings together key leaders in muscle biology. These experts provide state-of-the-art insights into the three forms of muscle--cardiac ..., Eric Manes Screenwriter / Producer & Co-Founder of luxury chocolate brand Coco Suisse Los Angeles, CA. Eric Manes Washington, DC. Eric Manes On-site service representative at Grainger ..., Mark then partnered with Eric Manes to produce a unique spirit called Hazelnut Rum, which contains a range of ingredients including vanilla, cinnamon, honey as well as real hazelnuts. Sugarland Distilling Company added the blend to their well-known series, followed by Digger Manes and Mark Ramsey's Apple Rye Brandy., May 4, 2024 · Have you ever wondered about Eric Manes' health problems? This article delves into the various health issues that Eric Manes has faced over the years. From his struggles with chronic conditions to his journey towards recovery, we will uncover the challenges that this individual has encountered on his path to wellness., Eric accompanies Russell when the King visits Queen Sophie-Anne's mansion. He physically coerces the Queen to agree to Russell's marriage proposal, and locks her in a cage. The next night Eric brings Hadley in front of Sophie-Anne and threatens to drain Hadley, unless she tells him why she is interested in Sookie., B is for blood flow. Blood flow is critical for brain health. Surprisingly, the blood vessels that feed our brain cells age faster than those neurons, so keeping your brain healthy means taking care of your blood vessels. A history of hypertension, heart disease, stroke, or a lack of physical exercise are risk factors for blood flow problems., Boom Time for Moonshine: With Eric 'Digger' Manes, Mark Ramsey, Brian, Josh Owens., Moonshiner Digger Blood Disease; ... Eric "Digger" Manes, widely recognized from the hit Discovery Channel series "Moonshiners," recently shared about his health struggles. ... The 13th season of "Moonshiners" kicked off earlier this month, coinciding with Digger Manes revealing his leukemia diagnosis. After watching the season's first episode ..., The reality TV star will probably pass on the time-honoured practice to his child- we expect to see his young lad on the show. Reality TV star facts report that Moonshiners Eric “Digger” Manes has a net worth of $300,000. With their ever increasing popularity, his net worth is expected to surge in subsequent years., Menkes disease is a genetic disorder that affects your body's ability to process copper. Symptoms include seizures, slow growth, floppy muscles and kinky (crinkly) hair. There isn't a cure for Menkes disease, but early treatment with copper can help reduce symptoms and prolong life. Contents Overview Symptoms and Causes Diagnosis and Tests ..., In the 2015 Philippine Cancer Facts & Estimates report, The Philippine Cancer Society has estimated that at least 4.5 per 100,000 Filipinos may develop leukemia. It also said that at least 4,270 ..., Marvin “Jim Tom” Hedrick, the colorful master distiller from Discovery's Moonshiners, passed away this morning, according to his co-stars Eric "Digger" Manes and Mark Ramsey., Components and extracts of Lion's Mane have proven antibiotic, anticancer, neuroprotective, fat- and glucose -lowering effects. This mushroom also protects against stomach ulcers, improves anxiety, cognitive function, and depression, and has anti- fatigue and anti-aging properties [ 6, 2 ]. All of these beneficial effects are based on three ..., Jan 26, 2022 ... The use of NPs in medicine is limited to nanopharmaceuticals and nanoimaging and blood disorders [46]. Smart nanomaterials (or Dynabeads) are ..., Mark and Digger's Big Test: Directed by Dean Bushala. With Jeremy Schwartz, Eric 'Digger' Manes, Mike Cockrell, Jerry Benson., Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. Typically, only one ear is affected initially, but over time, both ears may become involved. Episodes generally last from 20 minutes to a few hours. The time between episodes varies., There were an estimated 157,803 cerebrovascular-related deaths in 2003; 138,397 of which were in people age 65 and older. Cerebrovascular disease is the most common life-threatening neurological event in the U.S. Intracranial atherosclerosis is responsible for approximately 40,000 of these attacks per year, representing 10 percent of all ischemic strokes., Thalassemia. A low hemoglobin count can also be due to blood loss, which can occur because of: Bleeding in your digestive tract, such as from ulcers, cancers or hemorrhoids. Frequent blood donation. Heavy menstrual bleeding (heavy menstrual bleeding-although even normal menstrual bleeding may cause a slightly low hemoglobin count) Causes shown ..., Digger said he had a “rare blood disease” and didn’t have much time left. He went on to explain that he wanted to leave his mark on the world before he passed away. Later in the episode, it looked like they would show more about what is going on with Digger. It didn’t happen until the end of the episode. He explained that he has had the ..., Health & Illness Reports After Blood Disease After the recent release of the 13th season of Moonshiner, fans worldwide have expressed growing concerns about the health of Digger Manes, following reports of him being sick. Eric Digger Manes, an iconic figure in the moonshining realm, hails from the scenic hills of the Appalachian Mountains., A blood disorder is any disease that prevents your blood from working properly. It could mean you have too many or too few blood cells. Or a blood disorder can affect the way your blood clots, which is a bleeding disorder. Some blood disorders are blood cancers. There are many types of rare blood disorders, including:, Jan 8, 2024 · Eric "Digger" Manes, widely recognized from the hit Discovery Channel series "Moonshiners," recently shared about his health struggles. Many have questioned how sick is Digger on Moonshiners lately. He's mostly known by his nickname, Digger, and is a native of Newport, Tennessee., Expertise in rare conditions: We offer world-class care for rare cancers, such as neuroblastoma. Our team also gives hope for healing to children with uncommon blood diseases, such as hemophilia. Get more information about the conditions we treat. Team approach: For many conditions, multiple specialists come together to guide your child's care., I meet Eric Manes inside Fruit Jar Alley, his wife's clothing boutique in the sleepy Smoky Mountain town of Newport, Tennessee. Better known as "Digger" from the Discovery Channel docu-series Moonshiners, Manes is wearing overalls with the top button on each side undone, and doesn't look like someone of reality TV fame.But then again, Manes doesn't exactly line up with my expectation ..., The reality TV star will probably pass on the time-honoured practice to his child- we expect to see his young lad on the show. Reality TV star facts report that Moonshiners Eric “Digger” Manes has a net worth of $300,000. With their ever increasing popularity, his net worth is expected to surge in subsequent years., Eric LeGrand attended the event, which included a blood drive, and spoke about the need for more blood donations to fight sickle cell disease. The Mayor of Fairfield , William Galese was also in ..., To diagnose Graves' disease, your doctor may conduct a physical exam and check for signs and symptoms of Graves' disease. He or she may also discuss your medical and family history. Your doctor may also order tests including: Blood tests. Blood tests can help your doctor determine your levels of thyroid-stimulating hormone (TSH) — the ..., Rat studies have found that lion’s mane extract can speed up recovery from nervous system injuries, but research involving humans is lacking. 4. Protects against ulcers in the digestive tract ..., Eric LeGrand attended the event, which included a blood drive, and spoke about the need for more blood donations to fight sickle cell disease. The Mayor of Fairfield , William Galese was also in ..., Blood pressure regulation: Some studies have shown that Lion's Mane may help lower high blood pressure, a significant risk factor for heart disease. Cholesterol management: Animal studies have suggested that Lion's Mane may help improve lipid metabolism, leading to reduced levels of total cholesterol, low-density lipoprotein (LDL) cholesterol ..., Other parameters that the model incorporates are as follows: a G, a P: the production rates of G-CSF and platelets. a S (G), a w (G): The production rates of stem cells and white blood cells as functions of G-CSF concentration. f 1, f 2, f 3: Rates at which stem cells, white blood cells, and platelet concentrations down-regulate the stem cell ..., Eric Whitney (born April 15, 1991), known professionally as Ghostemane or Eric Ghoste, is an American singer, songwriter, rapper and musician. He has released eight solo albums and three collaborative albums under his Ghostemane moniker, primarily merging elements of heavy metal, hip hop and industrial music.Whitney has also released music with a number of additional solo projects, pursuing ..., Moonshiners: With Jeremy Schwartz, Josh Owens, Eric 'Digger' Manes, Mark Ramsey. Follows a diverse group of people living in Appalachia who carry on a 200-year-old tradition passed down from their forefathers, making moonshine.