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Acute pancreatitis refers to inflammation of the pancreas, causing sudden and severe abdominal pain. The pancreas is an organ that lies in the back of the mid-abdomen ( figure 1 ). It produces digestive juices and certain hormones, including insulin. Pancreatitis usually develops as a result of gallstones or moderate to heavy alcohol ...

Uptodate com. Generalized anxiety disorder (GAD) is characterized by excessive worry and anxiety that are difficult to control, cause significant distress and impairment, and occur on more days than not for at least six months [ 1 ]. GAD is a relatively common disorder, most often with an adult onset and chronic course [ 2-6 ].

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How do you make summer fun … for the kids AND yourself? Summer can be a stressful time for parents, so let’s share our best ideas for creating perfectly imperfect summer memories. ...Clostridioides difficile infection (CDI) is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients [ 1-3 ]. CDI is also increasingly diagnosed in younger patients and in the community.Anemia definitions — Anemia is defined for patient care as a reduction in one or more of the major red blood cell (RBC) measurements obtained as a part of the complete blood count (CBC): hemoglobin concentration, hematocrit, or RBC count. A low hemoglobin concentration and/or low hematocrit are the parameters most widely used to diagnose …Access clinical decision support on-the-go with UpToDate's mobile app. Get evidence-based answers to your medical questions anytime, anywhere. Learn more today.UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women ...Type 2 diabetes mellitus is a disorder that is known for disrupting the way your body uses glucose (sugar); it also causes other problems with the way your body stores and processes other forms of energy, including fat. All the cells in your body need sugar to work normally. Sugar gets into the cells with the help of a hormone called insulin.

UpToDate is a trusted and evidence-based clinical resource tool that provides comprehensive and updated information on various medical topics. Log in to access the full content and features of UpToDate, or register for a free trial or subscription. You receive the entire UpToDate library of specialties with your subscription. Click on a section below to view a detailed list of topics associated with that particular section. If you'd like to see the table of contents for other specialties, click here. Practice Changing UpDates. What's New. Patient Education. Calculators. Authors and Editors.UpToDate: Trusted, evidence-based solutions for modern healthcare. Dedicated to continuously innovating to meet the needs of the rapidly changing medical landscape, the UpToDate® suite offers clinical, drug, patient and member content to support health professionals wherever care takes place. Subscribe To UpToDate.Aeromonas species grow at a range of temperatures, although they are isolated with increasing frequency during warmer months (May through October in the Northern hemisphere). Aeromonas species cause a wide spectrum of disease syndromes among warm- and cold-blooded animals, including fish, reptiles, amphibians, mammals, and humans [ 3,4 ].INTRODUCTION. —. Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.

Smoking cessation is associated with clear health benefits. Cigarette smoking is the leading preventable cause of death in the United States and worldwide. Tobacco use increases the risk of many acute and chronic diseases, including cancers at many sites. Medications, including nicotine replacement, varenicline, and bupropion, …UpToDate® and the American Heart Association are collaborating to present select content abstracts on “What’s New in Cardiovascular Medicine.” UpToDate is an evidence-based, clinic...The prevention and treatment of iron deficiency is a major public health goal, especially in females, children, and individuals in low-income countries. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. This ...Intrauterine tamponade (with a balloon, packing, or vacuum) may be used to manage patients with postpartum hemorrhage (PPH) resulting from uterine atony that is not controlled by uterotonic medications and uterine massage. However, outcome data regarding vacuum-induced tamponade are limited.Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in …

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Beta-lactamases are enzymes that open the beta-lactam ring, inactivating the antibiotic. The first plasmid-mediated beta-lactamase in gram-negative bacteria was discovered in Greece in the 1960s. It was named TEM after the patient from whom it was isolated (Temoniera) [ 2 ]. Subsequently, a closely related enzyme was discovered and named TEM-2.Feb 27, 2024 ... GRAPHICS · - Microbiologic diagnosis necrotizing infection · - Necrotizing fasciitis versus pyoderma gangrenosum · - MRSA parenteral antibioti...Dec 11, 2023 · Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials. UpToDate offers clinical, drug, patient and member content to support health professionals wherever care takes place. Learn about the UpToDate suite, its expert editorial content, access options, research studies, CME, and innovation in AI.

In February 2020, the World Health Organization (WHO) designated the disease COVID-19, which stands for coronavirus disease 2019 [ 1 ]. The WHO declared an end to the COVID-19 global health emergency in May 2023, more than three years after its emergence. This topic will discuss the virology, epidemiology, and prevention of COVID-19.Enterococcal species can cause a variety of infections, including urinary tract infections, bacteremia, endocarditis, and meningitis. The antimicrobial agents available for treatment of enterococcal infection are reviewed here, followed by treatment approaches for clinical syndromes caused by enterococci. Other issues related to enterococci are ...If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username. Close Subscribe. Subscribe. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. About Us ...Mar 8, 2024 · Beta-lactamases are enzymes that open the beta-lactam ring, inactivating the antibiotic. The first plasmid-mediated beta-lactamase in gram-negative bacteria was discovered in Greece in the 1960s. It was named TEM after the patient from whom it was isolated (Temoniera) [ 2 ]. Subsequently, a closely related enzyme was discovered and named TEM-2. Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. Our approach to pharmacologic therapy in patients whose systolic blood pressure falls by more than 10 to 20 mmHg after changing from a seated to upright posture is as follows: Choice of pharmacologic therapy – The choice of therapy is generally the same as in patients without orthostatic blood pressure changes.UpToDate® registrants and Individual subscribers can now answer their clinical questions anytime, anywhere by downloading this app onto an Android™ phone or tablet. UpToDate is the leading clinical decision support resource with evidence-based clinical information – including drug topics and recommendations that clinicians rely on at the ...Jan 26, 2024 ... UpToDate · Sign in · Practice Changing UpDates · What's New · UpToDate Pathways · Settings. View Topic. Share. Font Size. Sm...Smoking cessation is associated with clear health benefits. Cigarette smoking is the leading preventable cause of death in the United States and worldwide. Tobacco use increases the risk of many acute and chronic diseases, including cancers at many sites. Medications, including nicotine replacement, varenicline, and bupropion, have demonstrated ...

UpToDate personal subscriptions support physicians with evidence-based clinical recommendations. With so much change in the world of patient care, it is clear that access to continuously updated and reliable data is critical for both provider and patient satisfaction. UpToDate® connects you to the most current medical research and findings ...

Smoking cessation is associated with clear health benefits. Cigarette smoking is the leading preventable cause of death in the United States and worldwide. Tobacco use increases the risk of many acute and chronic diseases, including cancers at many sites. Medications, including nicotine replacement, varenicline, and bupropion, …Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.CLINICAL MANIFESTATIONS. Major clinical features and organ involvement. Constitutional symptoms — Constitutional symptoms such as fatigue, fever, and weight loss are present in most patients with systemic lupus erythematosus (SLE) at some point during the course of the disease.UpToDate contributors generally avoid use of NSAIDs, or use them with particular caution and at reduced doses, in older adults and patients (regardless of age) with existing or increased risk for cardiovascular, GI, or kidney disease. Concurrent gastroprotection (eg, a proton pump inhibitor) may be warranted.Access clinical decision support on-the-go with UpToDate's mobile app. Get evidence-based answers to your medical questions anytime, anywhere. Learn more today.UpToDate® and the American Heart Association are collaborating to present select content abstracts on “What’s New in Cardiovascular Medicine.” UpToDate is an evidence-based, clinic...- Advantages and disadvantages of oral anticoagulants - LMW heparin dosing renal insufficiency (adults) - Anticoagulant dose adjustment in liver disease - Possible contraindications to anticoagulation - Standard dosing of DOACs - DOACs PK and drug interactions - Inhibitors and inducers of P-glycoprotein drug efflux - DOAC absorption …

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Jul 29, 2021 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. Symptoms and signs — Rhabdomyolysis is characterized clinically by the triad of myalgias, muscle weakness, and red to brown urine due to myoglobinuria [ 1 ]. Biochemically, several serum muscle enzymes are elevated, including CK. The degree of muscle pain and other symptoms varies widely. Most of the symptoms of rhabdomyolysis …UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials.Evidence-based medicine (EBM) is the care of patients using the best available research evidence to guide clinical decision-making ( figure 1) [ 1,2 ]. The value of EBM is heightened in light of the following considerations: The volume of evidence available to guide clinical decisions continues to grow at a rapid pace ( figure 2)UpToDate: Trusted, evidence-based solutions for modern healthcare. Dedicated to continuously innovating to meet the needs of the rapidly changing medical landscape, the UpToDate® suite offers clinical, drug, patient and member content to support health professionals wherever care takes place. Subscribe To UpToDate.UpToDate offers clinical, drug, patient and member content to support health professionals wherever care takes place. Learn about the UpToDate suite, its expert editorial content, access options, research studies, CME, and innovation in AI.Oct 25, 2023 · A table summarizing the emergency management of acute hyponatremia in adults is provided ( table 1 ). An alternative approach, recommended in by European organizations, is to treat with two 150 mL bolus infusions of 3 percent saline, each given over 20 minutes, measuring the serum sodium between infusions [ 28 ]. Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...Gastroesophageal reflux disease (GERD) is notable for its high prevalence, variety of clinical presentations, under-recognized morbidity, and substantial economic consequences. This topic will review the clinical manifestations and diagnosis of GERD. The pathophysiology and management of GERD are discussed in detail separately. ….

Outline · General approach · Lifestyle modification and good sleep hygiene · Withdrawal of causative medications · Treatment of co-occurring psychiatric...Trusted expert editorial content. The heart of UpToDate is over 7,400 expert clinicians, editors, and reviewers who review and assemble the latest evidence-based clinical, …Is it postpartum depression or baby blues? It's not the same condition! These are the symptoms of postnatal depression and how to manage them. Postpartum depression is a mental hea...UpToDate is a trusted and evidence-based clinical resource tool that provides comprehensive and updated information on various medical topics. Log in to access the full content and features of UpToDate, or register for a free trial or subscription.Feb 27, 2024 ... GRAPHICS · - Microbiologic diagnosis necrotizing infection · - Necrotizing fasciitis versus pyoderma gangrenosum · - MRSA parenteral antibioti...Conjunctivitis, also called "pink eye," is defined as an inflammation of the conjunctiva. The conjunctiva is the thin membrane that lines the inner surface of the eyelids and the whites of the eyes (called the sclera) ( figure 1 ). Conjunctivitis can affect children and adults. The most common symptoms of conjunctivitis include a red eye and ...Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …The prevention and treatment of iron deficiency is a major public health goal, especially in females, children, and individuals in low-income countries. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. This ... Uptodate com, Symptoms and signs — Rhabdomyolysis is characterized clinically by the triad of myalgias, muscle weakness, and red to brown urine due to myoglobinuria [ 1 ]. Biochemically, several serum muscle enzymes are elevated, including CK. The degree of muscle pain and other symptoms varies widely. Most of the symptoms of rhabdomyolysis are nonspecific., To learn more about UpToDate’s patient information, contact your UpToDate Account Manager or Customer Service. Tel: Email: 1-800-998-6374 [email protected] UpToDate, Inc. | 95 Sawyer Road | Waltham, MA 02453-3471 | www.uptodate.com ©UpToDate, Inc. 12/10 SKU#000250, Cellulitis — The most common symptom of cellulitis is dull pain or tenderness in the area of skin involvement. Other cellulitis symptoms can include swelling, warmth, and redness in a distinct area of skin. These symptoms commonly worsen, and the redness may expand over the course of hours to days. The onset of cellulitis may be …, Dec 11, 2023 · Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials. , UpToDate is a trusted online resource that provides reliable and current information on various medical topics. Whether you are a physician, a patient, or a student, you can sign in with your email, username, or organization account to access UpToDate's evidence-based answers to your clinical questions. , General symptoms — Thyroid hormone normally stimulates the metabolism, and most of the symptoms of hypothyroidism reflect slowing of metabolic processes. General symptoms may include fatigue, sluggishness, slight weight gain, and intolerance of cold temperatures. Skin — Hypothyroidism can decrease sweating., An overview of the approach to the prevention and treatment of osteoporosis in postmenopausal women will be presented here. The diagnosis and evaluation of osteoporosis in postmenopausal women and the management of osteoporosis in other patient groups are discussed separately. (See "Clinical manifestations, diagnosis, and …, INTRODUCTION. Pseudomonas aeruginosa is a key gram-negative aerobic bacillus in the differential diagnosis of a number of infections. This organism is important because it is often antibiotic resistant and can cause severe hospital-acquired infections associated with a high mortality rate, especially in immunocompromised hosts., Other manifestations include lower abdominal pain and cramping, low-grade fever, nausea, and anorexia [ 2,5 ]. Diarrhea may be associated with mucus or occult blood, but melena or hematochezia are rare. Fever is associated with CDI in about 15 percent of cases; temperature >38.5°C may occur in the setting of nonsevere or severe CDI., About UpToDate UpToDate is the evidence-based, point-of-care resource trusted for reliable clinical answers around the world. UpToDate incorporates the latest medical findings, the best available evidence, and practical recommendations for patient care — so whatever your clinical question, you can be sure to find the answers you need., Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here., The clinical features of KD reflect widespread inflammation of primarily medium-sized muscular arteries. Diagnosis is based upon evidence of systemic inflammation (eg, fever) in association with signs of mucocutaneous inflammation. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, rash, extremity ..., Generalized anxiety disorder (GAD) is characterized by excessive worry and anxiety that are difficult to control, cause significant distress and impairment, and occur on more days than not for at least six months [ 1 ]. GAD is a relatively common disorder, most often with an adult onset and chronic course [ 2-6 ]., Indices Commodities Currencies Stocks, Oral options include penicillin V potassium, amoxicillin, cephalexin, and cefadroxil. Parenteral options include cefazolin, nafcillin, and flucloxacillin. (See 'Treatment of erysipelas' above.) Duration of antibiotic therapy – We suggest five to six days of therapy rather than longer durations ( Grade 2C )., Using deep insights and evidence to solve a diagnostic puzzle. Learn how UpToDate helped a pediatric resident diagnose a rare case of neonatal diabetes mellitus. Clinical decision support (CDS) leverages peer-reviewed medical evidence to offer patients the best care. UpToDate continues to be the leading CDS solution used by healthcare providers., In some cases, heart failure can be mild and cause minor symptoms that are only evident with physical activity. Other times it can be severe (causing symptoms at rest) or even life-threatening. The most common symptoms of heart failure are shortness of breath, fatigue, leg swelling, and other signs of fluid retention., UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care., Moved Permanently. The document has moved here., Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options., Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …, The clinical approach to S. aureus bacteremia consists of careful history and physical examination, infectious disease consultation, and diagnostic evaluation including echocardiography and additional imaging as needed. History and physical examination. History – A careful history and physical examination is essential., Trusted for more than 30 years, UpToDate® is the clinical decision support resource that provides over 2 million medical professionals worldwide with the latest evidence-based information available across 25 specialties. With the ever-increasing complexity of diseases, medicine, and clinical practice in today's world, UpToDate is dedicated to ..., Moved Permanently. The document has moved here., Genital herpes is caused by infection with the herpes simplex virus (HSV, usually type 2). It can also be caused by herpes simplex virus type 1, which is the cause of oral herpes (cold sores on the mouth and lips). The spread of HSV is discussed below. (See 'Genital herpes transmission and risk factors' below.), The pharmacology, efficacy, contraindications, and side effects of metformin for the treatment of diabetes will be reviewed here. A general discussion of initial treatment of type 2 diabetes and the role of metformin in the prevention of diabetes, in the treatment of polycystic ovary syndrome, and in gestational diabetes are reviewed separately., UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide., UpToDate: Trusted, evidence-based solutions for modern healthcare. Dedicated to continuously innovating to meet the needs of the rapidly changing medical landscape, the UpToDate® suite offers clinical, drug, patient and member content to support health professionals wherever care takes place. Subscribe To UpToDate., Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username., UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. , UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care., UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language., Apr 5, 2024 ... Outline · - Respiratory/airborne transmission as primary route · - Minimal role of other person-to-person routes · - Viral shedding and period&...